Aikuisten tutkimukset
- HO156, AMLSG 28-18: A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapy (HOVON 156 AML)
- VenEx, FLG-V001: Open-Label Study of Venetoclax in Combination With Azacytidine in Acute Myeloid Leukemia Patients Selected Using Ex Vivo Drug Sensitivity Screening
- HO150, AMLSG 29-18: Open, multicenter, double-blind, randomized, placebo-controlled study of ivosidenib or enasidenib in combination with induction therapy and consolidation therapy followed by maintenance therapy in patients with newly diagnosed acute myeloid leukemia or myelodysplastic syndrome with excess blasts-2, with an IDH1 or IDH2 mutation, respectively, eligible for intensive chemotherapy
- DCOne-002, Advance II: An international, Multicentre, Open-label Study to Evaluate The Efficacy and Safety of Two Different Vaccination Regimens of Immunotherapy with Allogeneic Dendritic Cells, DCP-001, in Patients with Acute Myeloid Leukemia that are In Remission with Persistent MRD
- CPDR001X2105: Open-label study of PDR001 and/or MBG453 in combination with decitabine in patients with acute myeloid leukemia or high risk myelodysplastic syndrome
- CHDM201H12101C: Open-label study of HDM201 in combination with MBG453 or venetoclax in adult subjects with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS)
- RAMPP: Multicentric, Prospective, Randomized Controlled Trial Comparing Best Systemic Therapy (BST) With Radical Prostatectomy or BST Alone in the Management of Men With Pauci-metastatic Prostate Cancer
- SPCG-15: Primary Radical Prostatectomy Versus Primary Radiotherapy for Locally Advanced Prostate Cancer: an Open Randomized Clinical Trial
- PRIAS: Prostate cancer Research International: Active Surveillance - guideline and study for the expectant management of localized prostate cancer with curative intent
- ProScreen: A Randomized Trial of Early Detection of Clinically Significant Prostate Cancer
- HERO: randomized, open-label, parallel group efficacy and safety study to evaluate oral daily relugolix 120 mg to Leuprolide in patients with androgen-sensitive advanced prostate
- THORIUM PSMA: A Phase 1, open label, first in human, multi center, study to evaluate the safety, tolerability, pharmacokinetics and anti tumor activity of a thorium-227 labeled antibody-chelator conjugate BAY 2315497 injection, in patient with metastatic castration resitent prostate cancer
- CYPIDES: Safety and pharmacokinetics of ODM-208 in patients with metastatic castration-resistant prostate cancer
- STESIDES: Open, non-randomized, uncontrolled, multicenter dose-escalation, first-in-human study with a dose expansion. Safety and pharmacokinetics of ODM-209 in patients with metastatic castration-resistant prostate cancer or estrogen receptor- positive, HER2 negative advanced breast cancer
- SAKK 35/14: Rituximab with or without Ibrutinib for untreated patients with advanced follicular lymphoma in need of therapy. A randomized, double-blinded, SAKK and NLG collaborative Phase II trial
- TRIANGLE: Autologous Transplantation after rituximab/Ibrutinib/Ara-c containig induction generalized mantle cell lymphoma- a randomized European mcl network trial
- LYMRIT: A phase I/II study of lutetium (177Lu)-lilotomab satetraxetan (Betalutin®) antibody-radionuclide-conjugate for treatment of relapsed non-Hodgkin lymphoma
- JCAR: A phase 2, single-arm, multi-cohort, multi-center trial to determine the efficacy and safety of JCAR017 in adult subjects with aggressive B-cell Non-Hodgkin lymphoma
- CHRONOS-4: A phase III, randomized, double-blind, controlled, multicenter study of intravenous PI3K inhibitor copanlisib in combination with standard immunochemotherapy versus standard immunochemotherapy in patients with relapsed indolent non-Hodgkin's lymphoma (iNHL)- CHRonos-4
- BREBEN: A phase 1/2 study of combination of pixantrone, etoposide, bendamustine and in CD-20 positive tumors, rituximab in patients with relapsed aggressive non-Hodgkin lymphomas of B- or T- cell phenotype- The PREBEN study
- BIO-CHIC: Biomarker driven and dose intensified chemoimmunotherapy with early CNS prophylaxis in patients less than 65 years with high risk diffuse large B-cell lymphoma
- NP30179: A Multicenter, open-label, phase I study to evaluate the safety, tolerability and pharmacokinetics of escalating doses of RO7082859 as a single agent and in combination with obinutuzumab administered after a fixed, single dose pre-treatment of obinutuzumab ( Gazyva/ Gazyvaro ) in patient with relapsed / refractory B-cell Non Hodgin`s Lymphoma
- ENRICH: Randomised, open label study of Rituximab / Ibrutinib vs Rituximab / Chemotherapy in older patients with untreated mantle cell lymphoma
- BOLD: A Randomized Phase III Study Comparing Trastuzumab, Pertuzumab plus Docetaxel ( TPD) Followed by 3 Cycles of Chemotherapy to the Current Standard Regimen as the Treatments of Early HER2-positive Breast Cancer
- IMPASSION: A phase III, randomized, double-blind, placebo-controlled, multicentre study of the efficacy and safety of atezolizumab plus chemotherapy for patients with early relapsing recurrent (inoperable locally advanced or metastatic) triple-negative breast cancer
- BOLD: A Randomized Phase III Study Comparing Trastuzumab, Pertuzumab plus Docetaxel ( TPD) Followed by 3 Cycles of Chemotherapy to the Current Standard Regimen as the Treatments of Early HER2-positive Breast Cancer
- CLEE011A2207: A phase II, multicenter, randomized, open-label study to evaluate the safety and efficacy of 400mg of ribociclib in combination with non-steroidal aromatase inhibitors for the treatment of pre- and postmenopausal women with hormone receptor-positive, HER2 negative advanced breast cancer who received no prior therapy for advanced disease
- STESIDES: Open, non-randomized, uncontrolled, multicenter dose-escalation, first-in-human study with a dose expansion. Safety and pharmacokinetics of ODM-209 in patients with metastatic castration-resistant prostate cancer or estrogen receptor- positive, HER2 negative advanced breast cancer
- BORI: An open label, phase Ib, dose-escalation study evaluating the safety and tolerability of xentuzumab and abemaciclib in patients with locally advanced or metastatic solid tumors and in combination with endocrine therapy in patient with locally advenced or metastatic hormone receptor HER2-, breast cancer, followed by expansion cohorts
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